For those who may not know, Randall Munroe is the author of XKCD.

From https://en.wikipedia.org/wiki/Randall_Munroe :

In October 2010, Munroe’s fiancée was diagnosed with stage three breast cancer; there had been no prior family history.[51][52] The emotional effect of her illness was referenced in the comic panel “Emotion”, published 18 months later in April 2012.[53] In September 2011, he announced that they had married.[54] In November 2012, Munroe published a comic entitled “Two Years”, reflecting on their relationship since his wife’s breast cancer diagnosis.[55] He revisited the subject in December 2017 with a comic entitled “Seven Years”[56], in November 2020 in a comic entitled “Ten Years”[57], and again in November 2025 in a comic entitled “Fifteen Years”.[58]